Tuesday, September 24, 2019
Pauls prison epistles (Ephesians, Colossians, Philemon, and Research Paper
Pauls prison epistles (Ephesians, Colossians, Philemon, and Philippians) - Research Paper Example His fashion majorly credits his apostolic ability to Jesus Christ and the will of God. Evidence is in the wording and letter structure that is unique of all Paulââ¬â¢s writings. The epistle of Ephesians was written in Rome in A.D 60 (Walvoord & Zuck 434). This is well explained by the opening of the revelation of John of Patmos. The revelation shows that John was aware of Paulââ¬â¢s letters to seven centers of Christianity in which Ephesus was one of them. Another evidence is the letter known as ââ¬ËI Clementââ¬â¢ written in A.D 96 by Clement, Bishop of Rome to the church at Corinthian (Ackroyd 3). According to the salutation that Paul uses, the epistle was a general letter meant for several readers. In the opening greetings, Paul conveys his greetings to Godââ¬â¢s people at Ephesus while in some manuscript like in the beginning of chapter three, the word Ephesus is omitted and instead the word Gentiles is used. This shows that this letter was meant to be read in a number of churches in the province of Asia, of which Ephesus was one of them. The occasion for writing this latter is not clear since it does not have a specific audience. However, the book of acts brings out Paul as having spent a significant time on his last visit to Ephesus. In his time in Ephesus, he taught and baptized disciples, taught in the synagogue and the cities where he met a conflict with the pagans. It was in the same occasion that he did a speech of exhortation to the city elders. Therefore, the events mentioned could be suggested as the occasions that lead Paul to write this Epistle (BibleU 1). This letter was written when Paul was in prison in Rome. The supporting evidence is that it was sent together with the letter to Colossae, Philemon, and Philippians, which were all written in a Roman prison. In this letter there is no evidence of who he was with while writing this letter. According to Bruce (245), the epistle was written as an encouragement to
Monday, September 23, 2019
Operations Management Essay Example | Topics and Well Written Essays - 2500 words - 6
Operations Management - Essay Example SPC is also found to provide a new insight of relationships between quality and productivity performance measures (Colledani and Tolio, 2009). In addition, by the use of statistical methods, SPC can be a powerful technique for monitoring, managing and analyzing and improving process performance (Chen et al., 2008). Knowing these significant views of SPC and its linked benefits primarily in a manufacturing industry is a foundation of the idea that perhaps, this technique can also be employed even in way beyond the bound of manufacturing industries, especially if those industries have the intention to enhance or improve quality, cost, productivity, human resource management, and customer relationship. Regarding this, the work at hand builds a report substantiating the idea that SPC can also be useful in service industries. There are major claims that are presented in this report that are backed by existing research studies that have important link with the importance of SPC in the serv ice industries. ... Undeniably, services have become integral components of the industrial goods, as manufacturing goods and providing services have come in a package as a notable trend (Johansson and Olhager, 2006). Johansson and Olhager found that the common ground between manufacturing and service operations can be observed within the need to analyse volume, variety, and process issues. In other words, one important connection between service and manufacturing activities is found within the actual operation. The actual operation in the real world is wider in its scope, but this does not deny the idea that every firm operation may it for manufacturing or service industry must require a certain process. To consider productivity, the issue of volume or variety cannot be overlooked. In fact, both service and manufacturing activities have certain target goals to obtain certain level of productivity output. However, this does not stop with the consideration of productivity alone. Profitability is another c oncern of every firm that is either a part of the manufacturing or service industry. In the case of firms manufacturing or selling goods, after-sales services are found to affect companyââ¬â¢s profitability, customer retention and product development (Saccani et al., 2007). This finding reveals the thought that services can be the integral components of a manufacturing activity, and these two activities can therefore work to complement or support the other. Based on the cited information above, Saccani et al. would want to imply that in order to obtain profitability in the manufacturing industry, the need to consider after-sales services is a must. This is of great consideration, because establishing high-value for customers must
Sunday, September 22, 2019
Evaluation of Immigration Customs and Enforcement Budget Essay
Evaluation of Immigration Customs and Enforcement Budget - Essay Example ICE has estimated 15,000 employees of which 400 are in the domestic and 50 are in international offices The budget allocation goes to various departments depending on the activities carried out; homeland security investigations, enforcement and various operations in the office of state. ICE is involved in the local and tribal coordination, principal legal advisory, professional responsibility, immigration and customs enforcement, professional responsibility. ICE is the primary investigative arm of the department of homeland security. ICE is a key component of the DHS layered defense approach to protecting our nation. There are various subcommittees that deal with the jurisdiction over each agencyââ¬â¢s money and finance investigations, war and national defense statutes. There are more than 8,500 special Agents, making it the second largest federal law enforcement and criminal investigative agency .The urgency is headed by the office of the chief financial officer, Washington. ICE has the annual budget of more than $5.7 billion, the Management and administration activities for ICE. Executive Office of the President, Office of Management and Budget (2011) states that the Management and administration activities include executive overall leadership direction, strategic and policy development.The budget is authorized by different people that deal with the allocations of the resources. The proposed outlay for the agency include; Science and technology operational research and enhancement program $17.9M, supply chain secure corridors pilot project $9.8 air cargo project $ 16.1M and automated carry-on detection project $ 1.1M. The actual outlay overview involves E-verify and staffing, automatic threat recognition project $6.1m, viable bio particle capture project $2.1M, National Bio and Agro- Defense facility construction $150.0. According to Lake (2010), there are various political influences on the budget allocation in the ICE. Operation community
Saturday, September 21, 2019
Her body, her baby, her choice Essay Example for Free
Her body, her baby, her choice Essay Abortion, itââ¬â¢s not a choice that any woman would ever want to have to make, but itââ¬â¢s a decision that she should have the right to make. If it comes down to the possibility of her and her baby losing their lives, she should be able to stop this possibly fatal pregnancy. The body is hers, the baby is hers, and the choice should be hers. If you disagree, make the choice for your own body. Abortion should be legal. What people may not realize is that, legal or not, abortion still happens all around the world. Of the approximately 42 million abortions that do occur worldwide, almost half are performed by unskilled individuals, in environments that do not meet minimum medical standards or both. â⬠(http://www. guttmacher. org/pubs/gpr/12/4/gpr120402. html). Unsafe and illegal abortion is responsible for one in eight maternal deaths and according to an estimate done by the World Health Organization in 2006 ââ¬Ëback alleyââ¬â¢ abortions cause about 68,000 deaths each year where abortion isnââ¬â¢t legal. There is no question that making abortion illegal in places such as the United States, will only make these numbers increase greatly. Itââ¬â¢s no secret that raising a child requires mass amounts of money that many women who get pregnant donââ¬â¢t have, especially if they have no partner to help them out. Poor and low income women account for more than half of abortions in the United States. Without the option to get an abortion, there would be many more children suffering because they have to live their life in poverty. Almost half of all children with a single mother live in poverty, these children experience poverty at a rate that is more than four times higher than kids in married-couple families. Although, it is believed that ââ¬Å"abortion legalization may have led to an improvement in the average living conditions of children, probably by reducing the numbers of youngsters who would have lived in single-parent families, lived in poverty, received welfare and died as infants. â⬠(https://www. guttmacher. org/pubs/journals/3402502. html) Many people who are against abortion donââ¬â¢t take into consideration that not all women are able to safely give birth to a child and the risk of death associated with childbirth is about 10 times as high as the risk of death associated withà abortion. For example, teen girls aged around 15-19 years old have bodies that are not yet ready for childbirth. These girls are five times more likely to die, with around 70,000 of them dying annually. Their babies that do survive still have a 60% higher chance of dying than normal babies. With so much uncertainty, why shouldnââ¬â¢t they have the option to prevent themselves and their own parents the pain of losing a child. Many people believe that women are using abortion as a form of birth control. That they believe that they no longer need to be cautious because they can go pop over to the doctors to get an abortion whenever. However, this isnââ¬â¢t the case and, more often than not, women who get abortions were on some sort of birth control. Though, with any birth control there is almost always a chance of it not working properly and you becoming pregnant. Only less than one in ten women getting abortions werenââ¬â¢t on any sort of birth control. Making abortion illegal forces women who may have taken many precautions to not become pregnant to have a child that they donââ¬â¢t want and makes it so that an unwanted child is born into this world. This would not be fair to the woman or the child. Something that many people who oppose to abortion believe is that abortion, spontaneous or induced, raises the risk of breast cancer or any other type of cancer. There have been many, many studies done studies by various people such as the National Registry of Induced Abortions, the Danish Cancer Registry, Harvard researchers, and The California Teachers Study. The large size of most of the studies and the manner in which they were done provide good evidence that induced labor does not affect a womanââ¬â¢s risk of developing breast cancer. In 2003, the U. S. National Cancer Institute had a workshop with more than 100 of the worldââ¬â¢s leading experts who study pregnancy and breast cancer risk. They all found that neither induced or spontaneous abortion are linked to an increase in breast cancer risk; the level of scientific evidence for these findings was considered the highest level, ââ¬Ëwell establishedââ¬â¢. Abortion should be legal because it saves many womenââ¬â¢s lives from unsafe abortion, it can save families from lifelong poverty and it may save the lives of women who are unable to safely give birth to children. In a country that is based on freedom; freedom of speech, freedom of religion, individual freedom, why should this situation be any different? A law based off of a religious belief isnââ¬â¢t something that this country stands for, a law that prevents women from making decisions about her own body should not be a law in this country.
Friday, September 20, 2019
Ethics of Gene Mapping for Personalized Treatment
Ethics of Gene Mapping for Personalized Treatment There are many concerns about the future of the use of gene mapping for the personalisation of medicine. Whilst there are many benefits to the use of genetic testing to allow a more precise diagnosis and tailored treatments for various illnesses there is a risk of the information being abused to harm the patients. The information could be used to harm the patientââ¬â¢s future career prospects or lead to an increase in premiums for health insurance, possibly even an outright denial of coverage. However the US government has introduced legislation to protect the rights of the people and the concerns are outweighed by the benefits to the patientââ¬â¢s quality of life in terms of medical care. Introduction Mainstream medicineââ¬â¢s always had the differential diagnosis of patients decided primarily by generalisations made from a population of patients suffering from similar symptoms. The treatment is then found by knowledge acquired by research done over the entire population of people with similar symptoms(Torrey2013). The personalisation of medicine aims to have diagnosis and treatment tailored to patients to ensure they receive the best quality care possible. This will be done by the studying of their genetic framework to find out early if they have the genes for certain diseases. However, whilst itââ¬â¢ll be beneficial to the treatment of the patient, this has some ethical implications which this paper will aim to discuss throughout this paper and present a balanced argument to each concern as well as coming to a clear conclusion as to whether the benefits outweigh the ethical issues Method Relevant papers were found using medical journal databases subscribed to by both the University of Exeter and the University of Plymouth, the Google Scholar search engine, the BMJ, the NICE database for statistics and MEDLINE(PubMed). I also used Google to find relevant news articles relevant to my case to ensure I included public opinion as well as my own. The key words and phrases I used to search online for papers were various combinations of; ââ¬Å"genesâ⬠, ââ¬Å"gene mappingâ⬠, ââ¬Å"personalized treatmentâ⬠, ââ¬Å"discriminationâ⬠, ââ¬Å"cost toâ⬠and ââ¬Å"NHSâ⬠. I then narrowed my search to recent papers and news articles that were relevant to both the United Kingdom and the United States. Discussion What is gene mapping and how can it be used to personalize treatment? The Human Genome Project mapped the approximately 25,000 human genes, determining what genes exist in human DNA and what their roles are in a healthy human being. Knowledge of what those genes look and behave like when theyââ¬â¢re normal means that they can be compared with the genes of patients with medical problems to determine whether those patients genes are abnormal(Haga2009). Gene mapping is the process of finding the locations of genes on the chromosomes of patients(Haga2009). It used to be done by a process called linkage analysis, where the closer two genes are to each other, the more likely that theyââ¬â¢ll be inherited together(U.S. National Library of Medicineà ®2013). From this, patterns can be found, which can be used to determine their location on the chromosome(U.S. National Library of Medicineà ®2013). The more modern approach is by the use of small tags achieved by two methods. The first is by the use of genetic markers such as the products of a Polymerase Chain Reaction, where single piece of DNA can be amplified by the production of up to millions of copies of the DNA fragment(Bartlett Stirling2003). The second method is by use of enzymes specialised to bind to and cut very specific areas of DNA called restriction enzymes. The resulting fragments are separated by the process of electrophoresis and overlaps in the genetic information called contigs can be used to find consensus sequences which can be used to figure out which parts of the DNA strand it was originally from, which added together gives a map of the entire sequence(Gregory2005). Once gene mappingââ¬â¢s occurred, it can be used to several ways to personalise treatment for the patients. It can be used to further distinguish between various diseases to insure the patient receives the highest quality and most efficient care available. For example, research done at University College Londonââ¬â¢s found that there are three different locations on the DNA of patients afflicted with the disease Chrons Disease that were found to be coded for by genes(Elding et al.,2011). The three genes have different functions but were all found to be involved with the patient eventually developing Chrons Disease. This allows for further distinction between different types of Chrohns disease, meaning a further personalised course of treatment. This is similar to a result of the genomic profiling of breast cancer tumours. Four distinct types of breast cancer were found by were found by a research team at Cleveland University Hospital, meaning the cells of each subtype can be broken down and studied(University Hospitals Case Medical Center2013). By knowing the molecular underpinnings of a particular kind of breast cancer, the cure rates and, in the advanced disease setting quality of life and length of life can be improved.(University Hospitals Case Medical Center2013). Another way gene mapping can be used to personalise medicine is by the study of pharmacogenetics, the study of the impact of genetic variation and drug responses(Galas Hood2009). This is to customize the drug treatment and dosage to individual patients to get the most efficient and effective treatment possible. Itââ¬â¢d mean the treatment could work faster, cheaper, and fail less often, as thereââ¬â¢ll be no need to go through multiple treatments until they work(U.S. Department of Energy Human Genome Project2003). The use of personalised genetic medicine could save the NHS millions of pounds per year. Just purely with the disease of neonatal diabetes a reduce in cost was found as, $30,437 at 30 years, $12,528 at 10 years, and $23,227 at20 years compared to no genetic testing(Greeley et al.,2011). This is just one disease but putting into account all of the diseases this could be used for, overall millions could be saved for the NHS. Healthcare providers can personalise medicine to have more precise diagnoses, higher quality care, better therapies, and access to more precise patient information. Furthermore the genetic information taken can be added to large databases which can be shared with researchers and scientists worldwide.(The Genetic Information Nondiscrimination Act2008) They can use this information to take research forward at greater rates and will be beneficial. Ethical concerns Whilst there are many ways gene mapping can be beneficial to the treatment of patients, there are many concerns regarding how the process can be abused to violate the rights of the patients as well as have an overall negative result for the well being of the patient. One concern is how the genetic tests will be evaluated and regulated for accuracy, reliability, and utility.(Haga2009) Whilst the treatments will be tailored to the patients to a certain degree it can never be completely specialized. The human population that this treatment will be used for will still be quite a lot of people instead of just that specific person. This will mean the tests will still have some degree of generalisations made for populations leading to less accuracy and reliability in the treatments. There could be factors leading patients to no longer fit the assumptions such as underlying conditions or lifestyle that could reduce the effectiveness of the treatments. Furthermore whilst the populations will be large enough to have generalisations made, theyââ¬â¢ll be small enough to mean less reliable results. The sample size will be small meaning the results could be less accurate as smaller populations would be more unpredictable and less stable. Another concern is whether testing should be performed on patients suffering from incurable diseases. Pharmacogenetic testing could find gene expressions associated with an unknown disease for which no known treatment is known, or a disease thatââ¬â¢s known to be incurable(Guttmacher Collins2003). This could lead to the patient being upset about something theyââ¬â¢ve no control over and becoming depressed(Guttmacher Collins2003). Thereââ¬â¢s potential for a large amount of decrease in mental well-being for the patient as well as a decrease in quality of life due to this depression. However, whilst the disease is currently unknown, and no treatment has yet been formulated, it doesnt mean there wont be one found in the future. Despite there being no known treatment, or information at all, for diseases the genetic mapping could be useful in the future once a treatmentââ¬â¢s been found. Lastly the process of genetic mapping may be vital in identifying or finding a treatment for the disease. In fact, some people were found to be willing to undergo testing simply to further science, in hopes itââ¬â¢ll benefit their descendants.(G.I.N.A. 2008) Another major concern of the use of gene mapping is how the information gathered will be used and who has access to it. One fear thatââ¬â¢s commonly expressed is that the information could be used to harm people, for example, deny them access to health insurance, employment, education, and even loans. The information could be used to discriminate between patients seeking medical insurance by increasing the price of insurance if theyââ¬â¢re found to be susceptible to diseases, or completely deny them coverage. Insurers insist that they donââ¬â¢t currently perform genetic tests to obtain information, but the information should become available to them, citing the need to avoid moral hazard- the risk that patients who know theyââ¬â¢re susceptible to certain diseases will try and get insurance before they die at normal rates.(Torrey2010) Employers may deny jobs to potential employees or restrict hours they can work if theyââ¬â¢re found to be susceptible to diseases. They m ay even go as far as force early retirement on them if the potential for diseases are found whilst theyââ¬â¢re already working for them. However the US governmentââ¬â¢s put in place certain legislations to protect the rights of the people. The Genetic Information Non-discrimination Act (G.I.N.A.) of 2008 is an Act of Congress of the U.S.A. designed to stop the use of genetic information in health insurance and employment(Boston Business Journal2008) The act stops insurers from denying coverage, or charging unfair amounts based solely on information found via genetic testing showing a predisposition to developing the disease in the future(Boston Business Journal2008) The legislation also stops employers from being able to use information found from genetic testing when making decisions to do with the initial hiring of employees, the firing of employees, or any decisions concerning the employees position in the company such as promotions and demotions.(Boston Business Journal2008) The National Human Genome Research Institute(NHGRI) states that NHGRI believes that legislation that gives comprehensive protection against all forms of genetic discrimination is necessary to ensure that biomedical research continues to advance. Similarly, it believes that such legislation is necessary so that patients are comfortable availing themselves to genetic diagnostic tests. (Godfrey2012). Whilst the legislation is slightly overly broad and may lead to an increase in frivolous law suits, it can be made less ambiguous and protect the rights of the people to lessen concerns over the future of the use of genetic mapping to personalise medicine(Godfrey2012). Conclusion However despite these concerns I feel that the government, especially in the USA, is on the right tracks to providing clear legislation thatââ¬â¢ll protect the rights of people seeking to have genetic testing done with no repercussions on their lives. The legislations are fairly vague on some points but as the personalisation of medicine becomes more commonplace, a better idea of what the legislation will require can be formed and the legislation can be adjusted accordingly. I conclude that I feel cost benefits as well as the increase on quality of life for patients outweigh any major concerns about the genetic testing and concerns regarding how the information will be used and who has access to it is currently well established and there are currently measures put in place that protect the rights of people that can be adjusted as the use of gene mapping becomes more common. References
Thursday, September 19, 2019
Essay example --
Symbolism of the Lottery In Shirley Jacksonââ¬â¢s short story, ââ¬Å"The Lotteryâ⬠, she emphasizes on tradition in a small town, which has been drastically lost throughout the years. The community holds on to tradition due to the fear of superstition of the harvesting of the crops. Symbolism is ââ¬Å"the representation of something in symbolic form or the attribution of symbolic meaning or character to somethingâ⬠(Dictionary.com). The villagers show the unwillingness to challenge tradition and superstition. They might mumble about other villages that have done away with lotteries. Their traditional actions include having even the children of the condemned person throw stones; seem to ensure that this tradition of human sacrifice will continue into the foreseeable future. Shirley Jackson uses symbolism throughout the story with the black box, lottery itself and characters names to foreshadow the terrifying outcome of the lottery which is death. The first main symbol in the story is the black box. The black box symbolizes the darkness of ignorance that plagues the villagers of the community. They are reluctant to replace it even though itââ¬â¢s older than the oldest participating member of the lottery. Just as the community is unwilling to give up the ignorance of the old ways for the enlightenment of the new ways like some of the other communities have chosen to do. It also symbolizes the distraught tradition in the town and how it has changed over time. It is the center of the tradition because no matter how old and worn it gets, the villagers refuse to change it due to the tradition that it holds. The box has changed many of the villagersââ¬â¢s view of the lottery but no one can really remember how or why the tradition of the lottery began except to... ...in the story, the reasons for holding the lottery are long forgotten and the rituals connected to it. Other than the making of participant lists, the use of the old black box and the swearing in, have mostly fallen by the waste side. All that really remains is a rigid adherence to the ancient tradition of the town. The black box became the ultimate symbol of death, as it is the messenger that delivers the unfortunate winnerââ¬â¢s prize, which is death. The momentum that came from the villagersââ¬â¢ extreme degree of self-interest further propels the storm of immoral and unethical actions. The terrible tradition was carried out once again. Instead of considering the effect that the tradition had on their fellow villager, they were grateful that the little black box had spared them their own lives. As far as they were concerned the sky was blue and the sun was still shining.
Wednesday, September 18, 2019
Pet Sitting Service Essay -- essays research papers
Marketing Summary Plan WAGS TO WHISKERS PET SITTING SERVICE EXECUTIVE SUMMARY A service such as Wags to Whiskers Pet Sitting Service is very important to people who own animals. Pets are not merely animals to many people, but considered children. Knowing that a pet is being cared for in their own environment is a much sought after relief for many people. Wags to Whiskers offer a variety of services for an owner when it comes to caring for the pet while a person is away from the home. Items such as feed and watering, walking or exercise, and grooming are just a few of the services available. Cost for services will range from $5 to $35 depending upon the service and time frame needed to complete the service. The services can be used on a daily basis or for an extended amount of time when a person is out of town. Concentration on professionals and senior citizens will be the target audience to begin the Wags to Whiskers Pet Sitting Service. The area of concentration will include the three counties of Northern Kentucky, Boone, Kenton, and Campbell. Because owners feel guilty for leaving their pets alone for long periods, pet sitting services is one of the fastest growing businesses. If Wags to Whiskers has the perseverance, the opportunities are there for the making in the pet sitting business. This can be accomplished through multiple avenues of advertising, such as newspapers, vet offices, etc. Goals for Wags to Whiskers will consist of making $25,000 in the first year of business and growing in additional clientele, staff, and revenue over the next three years. PRODUCT DEFINITION Wags to Whiskers Pet Sitting Services offer clients who are busy working long hours away from home a much-needed peace of mind. It is important to the client to know the animal is well taken care of during their absence. Regardless of the type of pet Wags to Whiskers Pet Sitting Service offer feeding, watering, exercise and/or play, administer of medication, transportation to the vet, massages, and will make air travel arrangements for pets. According to Mary Jean Ballner who spoke at the NAPPS annual conference in January, 2005, ââ¬Å"Benefits (from massages) are the same as for humans (increases blood flow, releases endorphins, soothes) Benefits pet sitters by (accelerates bonding with all animals, aids with ââ¬Ëdifficultââ¬â¢ pets, relaxes scared animals).â⬠Other services offered... ... NAPPS to care for exotic animals 5.à à à à à Quarterly newsletter to clients and others to keep customers informed about services and products CONTROLS Monitoring Wags to Whiskers marketing plan will be an ongoing task. Advertisement will be important to track to determine who is providing the most new customers to Wags to Whiskers. Advertisements placed in the local newspapers should be checked quarterly to see if they are paying for themselves. If not, it will be necessary to find other avenues of advertising, such as pet magazines and the websites for the top three pet sitting organizations in the United States. If most of the new business is coming to Wags to Whiskers by word-of-mouth from current clients, it will be important to find a way to show appreciation, such as a free service for every new client received. Service fees could be a concern if business in the first six months is not on target to meet the first year revenue of $25,000. Improvement in this area may require looking at costs incurred compared to revenue coming in. Changes such as driving routes, time spent in traffic and time spent with pet must be reviewed for better efficiency.
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